County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, Room 212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856
E-Mail:acdc2@ph.lacounty.gov
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Acute Communicable Disease Control
Typhoid Fever, Acute
Typhoid fever, or “enteric fever,” is an acute systemic disease caused by the Gram-negative
bacillus Salmonella typhi. Transmission may occur person-to-person or by ingestion of
food or water contaminated by the urine or feces of acute cases or carriers. Common symptoms
include insidious onset of persistent fever, headache, malaise, anorexia, constipation
(more commonly than diarrhea), bradycardia, enlargement of the spleen, and rose spots on the
trunk. Humans are the only known reservoir for S. typhi. Vaccine is available to those at
high risk or travelers.